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: Activated SGK1 influences cell homeostasis, ion transport, and inhibits apoptosis by inactivating pro-apoptotic factors like 2. Clinical and Pathological Relevance

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SGK1 is a vital serine/threonine kinase that plays a pivotal role in how our cells respond to stress and hormonal signals. It is primarily regulated by stimuli like oxidative stress, heat shock, and hormones such as glucocorticoids and mineralocorticoids. 1. Role in Sodium Balance and Blood Pressure : Activated SGK1 influences cell homeostasis, ion transport,