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Usually a 32-bit vs. 64-bit DLL conflict. The new GTA5.exe is heavily reliant on C++ libraries. Fix:

Grand Theft Auto V (GTA V) is an action-adventure game developed by Rockstar North and published by Rockstar Games. It was first released in 2013 for PlayStation 3 and Xbox 360, and later for PlayStation 4, Xbox One, and Microsoft Windows.

You downloaded the new GTA5.exe . You launch the game. Disaster. Here are the top 3 errors and fixes.

Searching for a "gta5.exe new" download on third-party websites or shady forums is a major security risk.