Let’s address the elephant in the room immediately: The software is deeply integrated into the Windows operating system via COM components, registry entries, shared runtimes, and the .NET Framework. Visual Studio is arguably one of the most "non-portable" applications ever created.
If a primary development machine fails, a portable USB drive turns any temporary computer into a fully functional development workstation within seconds. Technical Limitations and Risks portable visual studio 2010 ultimate
Unlike modern text editors (think Notepad++ or Sublime Text), Visual Studio is a massive, system-dependent ecosystem. When you install VS 2010, it does much more than copy files to a folder: Let’s address the elephant in the room immediately: